Homologous genes, also known as Hox genes, determine where a cell should go in our bodies and what function it will perform.. It can form, for example, the chest, heart and wings of a bird, placing them in the correct anatomical positions.
It is important that these genes play a large role in our bodies.

According to scientists Hox genes are difficult to studyBecause they form clusters and do not contain repetitive elements characteristic of other parts of the genome. These factors simultaneously make its uniqueness a major challenge to science.

Scientists create long filaments Synthetic DNA By transcribing DNA from the genes of Hox mice. The DNA was then delivered to its exact location in mice pluripotent stem cells (Multipotent stem cells are cells that have the ability to differentiate into all types of cells and tissues that make up mammals). The use of two different types made it possible to distinguish between synthetic rat DNA and normal rat cells.

By putting synthetic Hox DNA into the cells of mice, it will allow us to study how this happens Hox genes help cells learn and remember a location in the body. In mammals, Hox gene clusters are flanked by regulatory regions that control how Hox genes are activated. Scientists do not yet know whether the block itself or the block with other elements is responsible for learning and remembering.

According to the researchers, gene sets contain all the information necessary to decode and remember a locus. This indicates that the compact nature of Hox groups allows us to know their location, confirming a thesis that was difficult to test before.

See also  An obstacle course and a mural commemorating the Krzysztof Comeda. Unique property in Wroclaw